Carson Watts Consulting - Chris Coggins, Ph.D., DABT - Board Certified Toxicologist Carson Watts Consulting - Chris Coggins, Ph.D., DABT - Board Certified Toxicologist
Carson Watts Consulting - Chris Coggins, Ph.D., DABT - Board Certified Toxicologist
Carson Watts Consulting
Chris Coggins, Ph.D., DABT - Board Certified Toxicologist
1266 Carson Watts Road, King, NC 27021-7453 USA (map)
336-983-7445 ... (Fax 7446) ... 336-416-0622 (World Cell)
"Inhalation Toxicology, General Toxicology, Toxicologic Pathology, Epidemiology"

Curriculum Vitae - Chris Coggins, Ph.D., DABT
( Education - Employment - Languages - Societies - Publications - Posters - Correspondence - Testimony - Reviewer )



NAMEChristopher Richard Emerson COGGINS
PLACE/DATE OF BIRTHCo. Durham, England; 14 March 1950
NATIONALITYBritish (Passport # 705221271)
Past holder of Swiss "C" permit. U.S. Work Permit # A28352948.
ADDRESSES

1266 Carson Watts Road,
King NC 27021-7453, U.S.A.
Tel. (336) 983-7445, Fax 983-7446
World Cell 336-416-0622
e-mail chris@carsonwattsconsulting.com
(Alternate: chris_coggins@hotmail.com)

Low Crag Farm
Lartington, Barnard Castle
County Durham DL12 9DJ, England
www.Lartingtonlamb.com

EDUCATION

Glasgow University, Scotland: B.Sc. (1968-1972).

Edinburgh University, Scotland: Ph.D. (1972-1976).

In November 1986, certified in General Toxicology by the American Board of Toxicology. Recertified in 1992, 1997, 2002 and 2007.

EMPLOYMENT

From January 2003, Principal in Carson Watts Consulting LLC, a consulting firm specializing in inhalation toxicology, general toxicology, toxicologic pathology, and epidemiology.

From May 2002 to December 2002, Senior Vice-President, Scientific Affairs, at:

Lorillard Tobacco Company
P.O. Box 10529
Greensboro NC 27404-0529

From December 1996 to May 2002, Senior Vice-President, Science and Technology, at Lorillard.

From August 1985 to November 1996:

Research & Development
R.J. Reynolds Tobacco Company
Winston-Salem, NC 27102

From December 1976 to July 1985:

Battelle-Geneva Research Center
7 Route de Drize
CH-1227 Carouge-Geneva
SWITZERLAND.

From January 1972 to November 1976:
Animal Diseases Research Association
408 Gilmerton Road
Edinburgh EH17 7JH
SCOTLAND

LANGUAGES

English mother tongue, French spoken and read, basic knowledge of Italian and German.


SOCIETIES

American Association for the Advancement of Science
American Association for Cancer Research
American Board of Toxicology (Diplomate)
American Industrial Hygiene Association
International Society of Regulatory Toxicology and Pharmacology
EUROTOX
Society for Risk Analysis
Society for Research on Nicotine and Tobacco
Society of Toxicologic Pathologists (Associate)
Society of Toxicology
Roundtable of Toxicology Consultants

PUBLICATIONS

Coggins, C.R.E. and Field, A.C. (1976). Diurnal variation in the chemical composition of plasma from lactating beef cattle on three dietary energy intakes. Journal of Agricultural Science, Cambridge. 86 : 595-602.

Coggins, C.R.E. and Field, A.C. (1977). Changes in plasma concentrations of glucose,
FFA, ketone bodies, thyroxine and insulin of lactating beef cows in relation to time of feeding and energy status. pp. 41-47, Blood profiles in Animal Production, Occasional Production No. 1, British Society of Animal Production.

Coggins, C.R.E., Fouillet, X.L.M., Lam, R. and Morgan, K.T. (1980). Cigarette smoke induced pathology of the rat respiratory tract. A comparison of the particulate and vapour phases. Toxicology 16: 83-101. [Abstract]

Baumgartner, H. and Coggins, C.R.E. (1980). Description of a continuous smoking inhalation machine for exposing small animals to tobacco smoke. Beiträge zur Tabakforschung International. 10: 169-174.[Abstract]

Coggins, C.R.E. (1981). Changes in the respiratory physiology of rats exposed to different phases of cigarette smoke. pp. 420-430, Proceedings of the 19th Annual Hanford Life Sciences Symposium, Pulmonary Toxicology of Respirable Particles., 1979.

Coggins, C.R.E., Duchosal, F., Musy, C. and Ventrone, R. (1981). Measurement of respiratory patterns in rodents, using whole body plethysmography and a pneumotachograph. Laboratory Animals. 15: 137-140.

Musy, C., Morgan, K.T. and Coggins, C.R.E. (1981). Computerization of data capture for mouse skin painting studies. International Journal of Biomedical Computing. 12: 419-431.

Coggins, C.R.E., Musy, C. and Ventrone, R. (1982). Changes in the minute ventilation of rats exposed to different concentrations of tobacco smoke. Toxicology Letters. 11: 181-185. [Abstract]

Coggins, C.R.E., Lam, R. and Morgan, K.T. (1982). Chronic inhalation study in rats, using cigarettes containing different amounts of Cytrel tobacco supplement. Toxicology. 22: 287-296. [Abstract]

Coggins, C.R.E., Haroz, R.K., Lam, R. and Morgan, K.T. (1982). The tumourigenicity of smoke condensates from cigarettes containing different amounts of Cytrel, as assessed by mouse skin painting. Toxicology. 23: 177-185. [Abstract]

Ventrone, R., Baán, E. and Coggins, C.R.E. (1982). A novel inhalation device for the simultaneous anesthesia of several laboratory animals. Laboratory Animals. 16: 231-233.

White, R.R. and Coggins, C.R.E. (1982). Effects of smoke on elastase-induced emphysema. American Review of Respiratory Disease. 125: 214 (abstract).

Ringrose, A.R., Crawley, F.E.H. and Coggins, C.R.E. (1984). An automatic device for the addition of precise amounts of radiolabel to cigarettes. Beiträge zur Tabakforschung International. 12: 117-121. [Abstract]

Musy, C. and Coggins, C.R.E. (1984). A program for handling data obtained by 'blind' histopathological evaluations. International Journal of Biomedical Computing. 15: 285-302.

Ventrone, R., Musy, C. and Coggins, C.R.E. (1984). A method for producing forced expirograms in laboratory animals. Laboratory Animals. 18: 379-382.

Musy, C., Gatz, R.N., Coggins, C.R.E. and Ventrone, R. (1985). On-line data acquisition and control in a physiology laboratory. International Journal of Biomedical Computing. 17: 89-98.

Coggins, C.R.E., Ayres, P.H., Mosberg, A.T., Burger, G.T., Sagartz, J.W. and Hayes, A.W. (1989). Comparative inhalation study in rats, using a second prototype of a cigarette that heats rather than burns tobacco. Inhalation Toxicology. 1: 197-226.

Coggins, C.R.E., Ayres, P.H., Mosberg, A.T., Sagartz, J.W., Burger, G.T. and Hayes, A.W. (1989). Ninety-day inhalation study in rats, comparing smoke from cigarettes that heat tobacco with those that burn tobacco. Fundamental and Applied Toxicology. 13: 460-483. [Abstract]

Ayres, P.H., Mosberg, A.T., Burger, G.T., Hayes, A.W., Sagartz, J.W. and Coggins, C.R.E. (1989). Nose-only exposure of rats to carbon monoxide. Inhalation Toxicology. 1: 349-363.

Suber, R.L., Deskin, R., Nikiforov, A.I., Fouillet, X. and Coggins, C.R.E. (1989). Subchronic nose-only inhalation study of propylene glycol in Sprague-Dawley rats. Food and Cosmetic Toxicology. 27: 573-583. [Abstract]

Burger, G.T., Renne, R.A., Sagartz, J.W., Ayres, P.H., Coggins, C.R.E., Mosberg, A.T. and Hayes, A.W. (1989). Histologic changes in the respiratory tract induced by inhalation of xenobiotics: Physiologic adaptation or toxicity ? Toxicology and Applied Pharmacology. 101: 521-542. [Abstract]

Lee, C.K., Brown, B.G., Reed, E.A., Lowe, G.D., McKarns, S.C., Fulp, C.W., Coggins, C.R.E., Ayres, P.H. and Doolittle, D.J. (1990). Analysis of cytogenetic effects in bone marrow cells of rats subchronically exposed to smoke from cigarettes which burn or heat tobacco. Mutation Research. 240: 251-257. [Abstract]

Wehner, A.P., Renne, R.A., Greenspan, B.J., DeFord, H.S., Ragan, H.A., Westerberg, R.B., Wright, C.W., Buschbom, R.A., Burger, G.T., Hayes, A.W., Coggins, C.R.E. and Mosberg, A.T. (1990). Comparative subchronic inhalation bioassay in hamsters of a cigarette which only heats tobacco. Inhalation Toxicology. 2: 255-283.

Coggins, C.R.E., Doolittle, D.J., Lee, C.K, Ayres, P.H., Mosberg, A.T., Bolin, D.C., Burger, G.T. and Hayes, A.W. (1990). Histopathology, urine mutagenicity and bone marrow cytogenetics of mice exposed nose-only to smoke from cigarettes which burn or heat tobacco. Inhalation Toxicology. 2: 407-429.

Ayres, P.H., Mosberg, A.T. and Coggins, C.R.E. (1990). Modernization of nose-only smoking machines for use in animal inhalation studies. Journal of the American College of Toxicology. 9: 441-446.

Shreve, W.K., Ayres, P.H. and Coggins, C.R.E. (1991). Feasibility of using a near-infrared device for the estimation of nicotine presented to animals in inhalation studies. Toxicology Methods. 1: 84-88.

Sagartz, J.W., Madarasz, A.J., Forsell, M.A., Ayres, P.H., Burger, G.T. and Coggins, C.R.E. (1992). Histologic sectioning of the rodent larynx for inhalation toxicity testing. Toxicologic Pathology 20: 118-121. [Abstract]

Coggins, C.R.E., Ayres, P.H., Mosberg, A.T., Ogden, M.W., Hayes, A.W. and Sagartz, J.W. (1992). Fourteen-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. I. Inhalation toxicology; histopathology. Fundamental and Applied Toxicology 19: 133-140. [Abstract]

Lee, C.K., Brown, B.G., Reed, E.A, Rahn, C.A., Coggins, C.R.E. and Doolittle, D.J. (1992). Fourteen-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. II. DNA Adducts; alveolar macrophage cytogenetics. Fundamental and Applied Toxicology 19: 141-146. [Abstract]

Coggins, C.R.E., Ayres, P.H., Mosberg, A.T., Sagartz, J.W. and Hayes, A.W. (1993). Subchronic inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. Inhalation Toxicology 5: 77-96.

Lee, C.K., Brown, B.G., Reed, E.A., Coggins, C.R.E., Doolittle, D.J. and Hayes, A.W. (1993). Ninety-day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette: DNA adducts and alveolar macrophage cytogenetics. Fundamental and Applied Toxicology. 20: 393-401. [Abstract]

Coggins, C.R.E., Mosberg, A.T., Ayres, P.H., Sagartz, J.W. and Hayes, A.W. (1993). Comparative inhalation study in rats, using cigarettes containing tobacco expanded with CFC-11 or HCFC-123. Inhalation Toxicology. 5: 97-115.

Coggins, C.R.E., Ayres, P.H., Mosberg, A.T. and Wagner, B.M. (1994). Subchronic inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. The FASEB Journal 8: A 405.

Coggins, C.R.E. Subchronic inhalation studies in rats, using aged and diluted sidestream smoke from reference cigarettes. pp. 501-503 in Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. U. Mohr, Editor in Chief; Editors D.L. Dungworth, J.L. Mauderly and G. Oberdörster. ILSI Press, Washington, DC, 1994.

Coggins, C.R.E. Comparative inhalation studies in rodents, using smoke from cigarettes that heat rather than burn tobacco. pp. 505-507 in Toxic and Carcinogenic Effects of Solid Particles in the Respiratory Tract. U. Mohr, Editor in Chief; Editors D.L. Dungworth, J.L. Mauderly and G. Oberdörster. ILSI Press, Washington, DC, 1994.

Ayres, P.H., Mosberg, A.T. and Coggins, C.R.E. (1994). Design, construction and operation of an inhalation system for exposing laboratory animals to environmental tobacco smoke. American Industrial Hygiene Association Journal. 55: 806-810. [Abstract]

Lovejoy, H.M., McGuirt, W.F., Ayres, P.H., Hayes, A.W., Coggins, C.R.E., Sagartz, J.W. (1994). Effects of low humidity on the rat middle ear. The Laryngoscope 104: 1055-1058.

Reed, B.A., Lee, C.K., Brown, B.G., Coggins, C.R.E., Hayes, A.W. and Doolittle, D.J. Cytogenetic studies in laboratory animals exposed by inhalation to mainstream smoke or environmental tobacco smoke. pp. 362-379 in Chromosomal Alterations. Editors G. Obe and A.T. Natajaran. Springer-Verlag, Berlin, 1994.

Witschi, H., Pinkerton, K.E., Coggins, C.R.E., Penn, A. and Gori, G.B. (1995). Environmental tobacco smoke: experimental facts and societal issues. Fundamental and Applied Toxicology. 24: 3-12. [Abstract]

Ayres, P.H., McKarns, S.C., Coggins, C.R.E., Doolittle, D.J., Sagartz, J.E., Payne, V.M. and Mosberg, A.T. (1995). Replicative DNA synthesis in tissues of the rat exposed to aged and diluted sidestream smoke. Inhalation Toxicology 7: 1225-1246.

Coggins, C.R.E. (1996). The OSHA review of animal inhalation studies with environmental tobacco smoke. Inhalation Toxicology 8: 819-830.

Coggins, C.R.E., Lovejoy, H.M., McGuirt, F.M., Sagartz, J.W., Hayes, A.W. and Ayres, P.H. (1997). Relevant exposure to environmental tobacco smoke surrogate does not produce or modify secretory otitis media in the rat. Toxicologic Pathology 25: 395-397. [Abstract]

Coggins, C.R.E. (1998). A review of chronic inhalation studies with mainstream cigarette smoke in rats and mice. Toxicologic Pathology 26: 307-314.[Abstract]

Coggins, C.R.E. (2001). A review of chronic inhalation studies with mainstream cigarette smoke, in hamsters, dogs, and non-human primates. Toxicologic Pathology 29: 550-557. [Abstract]

Coggins, C.R.E. (2002). A minireview of chronic animal inhalation studies with mainstream cigarette smoke. Inhalation Toxicology 14 (10): 991-1002. [Abstract]

Heck, J.D., Misra, M., Coggins, C.R.E. (2002). The toxicological assessment of tobacco products: in vivo approaches. Recent Advances in Tobacco Science. 28: 137-165.

Coggins, C.R.E. (2003). Mesothelioma. Toxicologic Pathology 31 (1): 171. [Abstract]

Stinn, W., Teredesai,A., Kuhl, P., Knörr-Wittmann, C., Kindt, R., Coggins, C.R.E., and Haussmann, H.-J (2005). Mechanisms involved in A/J mouse lung tumorigenesis induced by inhalation of an environmental tobacco smoke surrogate. Inhalation Toxicology 17 (6): 263-276. [Abstract]

Stinn, W., Teredesai, A., Anskeit, E., Kuhl, P., Reininghaus, W., Rustemeier, K., Schepers, G., Schnell, P., Carchman, R.A., Coggins, C.R.E., and Haussmann, H.-J. Chronic nose-only inhalation study in rats, comparing room-aged sidestream smoke and diesel engine exhaust. Inhalation Toxicology 17 (11) 549-576. [Abstract]

Coggins, C.R.E. (2006). Oxidative stress in laboratory animals exposed to cigarette smoke, with special reference to chronic obstructive pulmonary disease. Chapter 11 in Cigarette smoke and oxidative stress. Eds. B.B. Halliwell and H.E. Poulsen. Springer, Berlin.

Schleef, R.R., Vanscheeuwijck, P.M., Schlage, W.K., Borzelleca, J.F., Coggins, C.R.E., and Haussmann, H.-J. (2006). Animal models for three major cigarette-smoke-induced diseases. Chapter 33 in Inhalation Toxicology. Second Edition. Eds. H. Salem and S.A. Katz. CRC Press, Boca Raton.

Werley, M.S., Coggins, C.R.E., and Lee, P.N. (2007). Possible effects on smokers of cigarette mentholation: A review of the evidence relating to key research questions. Regulatory Toxicology and Pharmacology (3) 189-203.[Abstract]

Lemus, R., Carmines, E.L., Van Miert, E., Coggins, C.R.E., Anskeit, E., Gerstenberg, B., Meisgen, T.J., Schramke, H., Stabbert, R., Völkel, H., and Terpstra, P.M. (2007). Toxicological comparisons of cigarettes containing different amounts of vanillin. Inhalation Toxicology. (8), 683-700.[Abstract]

Coggins, C.R.E. (2007). Inhalation studies with cigarette smoke in laboratory animals. International Journal of Toxicology 26 (4), 331-338. [Abstract]

Gaworski, C.L., Coggins, C.R.E., and Carmines, E.L. (2008). Palladium alters cigarette smoke toxicological profile, but accumulates in the lungs of rodents during inhalation exposure. Inhalation Toxicology [Abstract]. 20 (2) 167-182.

Coggins, C.R.E., and Gaworski, C.L. (2008). Could charcoal filtration of cigarette smoke reduce smoking-induced disease? A review of the literature. Regulatory Toxicology and Pharmacology 50: 359-365 [Abstract].

Patskan, G.J., Podraza, K.F., Meurrens, K., Coggins, C.R.E., Friedrichs, B., Gerstenberg, B., Gomm, W., Schnell, P., Stabbert, R., Veltel, D., Weber, S. and Terpstra, P. (2008). Toxicological comparisons of three styles of a commercial U.S. cigarette (Marlboro®) with the 1R4F reference cigarette [Abstract].  Inhalation Toxicology 20 (7) 695-721.

Werley, M.S., Freelin, S.A., Gerstenberger, B., Roemer, E., Vanscheeuwijck, P.M., Schramke, H., Van Miert, E., Weber, S., and Coggins, C.R.E. (2008).  Non-clinical evaluations of a second-generation Electrically Heated Cigarette (EHC) as a Potentially Reduced Exposure Product (PREP).  Regulatory Toxicology and Pharmacology (in press).

POSTERS


C.R.E. Coggins, R.N. Gatz, R. Ventrone and R.R. White. The use of pulmonary function tests for the detection of SO 2-induced bronchitis in the rat. 4th Congress of the European Society of Pneumonology, Milan, 1985.

C.R.E. Coggins. Changes in the minute ventilation of rats exposed to the vapor phase of diluted cigarette smoke. 25th Annual Meeting of the Society of Toxicology, New Orleans, LA, 1986 (The Toxicologist, 6: 208).

P.H. Ayres, C.R.E. Coggins and A.T. Mosberg. Cardiomegaly in rats after a 14-day exposure to sublethal concentrations of carbon monoxide. 26th Annual Meeting of the Society of Toxicology, Washington, D.C., 1987 (The Toxicologist, 7: 753), International Symposium on Extrapolation Modeling of Inhaled Gases and Vapors, Duke University, NC, 1987.

A.T. Mosberg, P.H. Ayres and C.R.E. Coggins. Pulmonary function effects in rats exposed to sublethal concentrations of carbon monoxide. 26th Annual Meeting of the Society of Toxicology, Washington, D.C., 1987 (The Toxicologist, 7 : 752), International Symposium on Extrapolation Modeling of Inhaled Gases and Vapors, Duke University, NC, 1987.

A.T. Mosberg, C.R.E. Coggins and P.H. Ayres. Absorption and elimination kinetics in rats exposed to sublethal concentrations of carbon monoxide. 26th Annual Meeting of the Society of Toxicology, Washington, D.C., 1987 (The Toxicologist, 7: 751), International Symposium on Extrapolation Modeling of Inhaled Gases and Vapors, Duke University, NC, 1987.

C.R.E. Coggins, G.T. Burger, P.H. Ayres and A.T. Mosberg. Histopathological changes in rats exposed to carbon monoxide. 26th Annual Meeting of the Society of Toxicology, Washington D.C., 1987 (The Toxicologist, 7: 754), 6th Annual Symposium of the Society of Toxicologic Pathologists, Philadelphia, PA, June 1987, International Symposium on Extrapolation Modeling of Inhaled Gases and Vapors, Duke University, NC, October 1987.

R.L. Suber, A.I. Nikiforov, X.L.M. Fouillet, R. Deskin and C.R.E. Coggins. Subchronic nose-only inhalation study of propylene glycol in Sprague-Dawley rats. 26th Annual Meeting of the Society of Toxicology, Washington, D.C., 1987 (The Toxicologist, 7: 758).

A.W. Hayes, C.R.E. Coggins, P.H. Ayres, G.T. Burger and A.T. Mosberg. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 1. Cigarettes, Experimental design. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1006).

R.A. James, J.T. Avalos, A.T. Mosberg, C.R.E. Coggins and P.H. Ayres. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 2. Nose-only inhalation system; smoke chemistry. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1007).

C.R.E. Coggins, A.T. Mosberg, G.T. Burger, A.W. Hayes and P.H. Ayres. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 3. Blood Composition. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1008).

A.T. Mosberg, C.R.E. Coggins, G.T. Burger, A.W. Hayes, R.L. Phelps, S.A. Reynolds and P.H. Ayres. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 4. Minute Ventilation. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1009).

P.H. Ayres, C.R.E. Coggins, G.T. Burger, A.W. Hayes, L. Gerald and A.T. Mosberg. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 5. Body weight change, organ weights. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1010).

G.T. Burger, C.R.E. Coggins, A.W. Hayes, P.H. Ayres, A.T. Mosberg and J.W. Sagartz. Ninety-day inhalation study in rats, comparing smoke from cigarettes which burned or only heated tobacco. 6. Histopathology. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1011).

L. Gerald, P.H. Ayres, A.T. Mosberg, A.W. Hayes, G.T. Burger, J.W. Sagartz and C.R.E. Coggins. Extended inhalation exposures of rats to cigarette smoke. 27th Annual Meeting of the Society of Toxicology, Dallas, TX, 1988 (The Toxicologist, 8: 1014).

A.T. Mosberg, C.R.E. Coggins, P.H. Ayres and A.P. Wehner. Relationships between amounts of nicotine presented and inhaled, and resulting plasma concentrations, in 90-day inhalation studies in rats. 28th Annual Meeting of the Society of Toxicology, Atlanta, GA, 1989. (The Toxicologist 9: 555).

C.R.E. Coggins, P.H. Ayres, A.T. Mosberg and C.H. Chen. The use of a lipid profile in a 90-day inhalation experiment in rats, comparing smoke from cigarettes which burned or which only heated tobacco. 28th Annual Meeting of the Society of Toxicology, Atlanta, GA, 1989.(The Toxicologist, 9: 553).

C.K. Lee, B.G. Brown, E.A. Reed, G.D. Lowe, C.W. Fulp, S.C. McKarns, C.R.E. Coggins, P.H. Ayres and D.J. Doolittle. Analysis of cytogenetic effects in bone marrow cells of rats subchronically exposed to smoke from cigarettes which burn or only heat tobacco. 28th Annual Meeting of the Society of Toxicology, Atlanta, GA, 1989 (The Toxicologist 9: 924).

P.H. Ayres, C.R.E. Coggins, J.W. Sagartz and G.T. Burger. Induction and regression of lesions in the rat larynx after acute exposure to smoke from 1R4F cigarettes. 28th Annual Meeting of the Society of Toxicology, Atlanta, GA, February 1989 (The Toxicologist, 9: 554), VIII International Symposium of the Society of Toxicologic Pathologists, Cincinnati, 1989.

C.K. Lee, B.G. Brown, D.J. Doolittle, D.C. Bolin, P.H. Ayres, G.T. Burger, A.W. Hayes and C.R.E. Coggins. Cytogenetic study in bone marrow cells of mice exposed by nose-only inhalation to smoke from cigarettes which burn or only heat tobacco. 29th Annual Meeting of the Society of Toxicology, Miami, FL, 1990. (The Toxicologist 10, 384), Relevance of animal studies to human risk assessment (University of Texas / M.D. Anderson Science Park; December 1990).

C.R.E. Coggins, A.T. Mosberg, P.H. Ayres, J.W. Sagartz, G.T. Burger and A.W. Hayes. Inhalation comparison in rats of menthol cigarettes which burn or which only heat tobacco. 29th Annual Meeting of the Society of Toxicology, Miami, FL, 1990. (The Toxicologist 10, 800).
D.W. Bombick, P.H. Ayres, P.R. Nelson, C.R.E. Coggins, D. France, C. Fulp, C. Lee and D.J. Doolittle. Assessment of the biological activity of mainstream smoke or environmental tobacco smoke (ETS) using a cellular smoke exposure technique. 1991 Annual Meeting of the Environmental Mutagen Society (Orlando, FL).

J.W. Sagartz, A.J. Madarasz, M.A. Forsell, P.H. Ayres, G.T. Burger and C.R.E. Coggins, Histologic sectioning of the rodent larynx for inhalation toxicity testing. 1991 Annual Meeting of the Society for Toxicologic Pathology, Monterey, CA.

P.H. Ayres, W.K. Shreve and C.R.E. Coggins. Flow cytometric quantitation of clearance and macrophage burden of inhaled polystyrene latex beads in rodents. 30th Annual Meeting of the Society of Toxicology, Seattle, WA, 1991. (The Toxicologist 12, 1005).

A.T. Mosberg, C.R.E. Coggins, P.H. Ayres, J.W. Sagartz and A.W. Hayes. Comparative inhalation study in rats, using cigarettes containing tobacco expanded with CFC-11 or HCFC-123. 30th Annual Meeting of the Society of Toxicology, Seattle, WA., 1991 (The Toxicologist 12, 1403).

C.R.E. Coggins, P.H. Ayres, A.T. Mosberg, M.W. Ogden, D.J. Doolittle, C.K. Lee, J.W. Sagartz and A.W. Hayes. 14-Day inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. 30th Annual Meeting of the Society of Toxicology, Seattle, WA., 1991. (The Toxicologist, 12, 1402).

K-M. Chang, G. Gentry, R. Davis, M. Stiles and C.R.E. Coggins. Determination of plasma nicotine and cotinine in rats exposed to aged and diluted sidestream smoke, using an enzyme-linked immunosorbent assay (ELISA). 30th Annual Meeting of the Society of Toxicology, Seattle, WA., 1991. (The Toxicologist, 12, 1003).

C.R.E. Coggins, J.W. Sagartz, P.H. Ayres, A.T. Mosberg and A.W. Hayes. Subchronic inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. 32nd Annual Meeting of the Society of Toxicology, New Orleans, LA. 1993 (The Toxicologist 13, 84).

C.R.E. Coggins, P.H. Ayres, A.T. Mosberg and M.W. Ogden. Aerosol characterization in a sub-chronic inhalation study in rats, using aged and diluted sidestream smoke from a reference cigarette. Paper 94-473, presented at the Fourth International Aerosol Conference, Los Angeles, CA, 1994.

CORRESPONDENCE


Coggins, C.R.E. and Steichen, T.J. (1993). Active and passive smoking and pathological indicators of lung cancer- a report of limited value? Journal of the American Medical Association 270: 1689-90.

Coggins, C.R.E. (1993). The hazards of active -- and passive -- smoking. The New England Journal of Medicine 329: 1580.

Coggins, C.R.E. (1994). Sidestream cigarette smoke. Circulation 89: 2943.

Coggins, C.R.E. (1996). Estimating Exposure to Environmental Tobacco Smoke. Journal of the American Medical Association. 276: 603.

Coggins, C.R.E. (1997). 1, 3-butadiene and environmental tobacco smoke. Circulation 95: 275.

Coggins, C.R.E. (1998). A prospective study of passive smoking and coronary heart disease. Circulation 97: 1871-1872.

Coggins, C.R.E. (2000). A review of chronic inhalation studies with mainstream cigarette smoke in rats and mice (Letter to the Editor). Toxicologic Pathology 28: 754.


TESTIMONY


September 21, 1993, presentation to the Occupational Safety & Health Administration, entitled "Case Studies in Carcinogenic Risk. Environmental Tobacco Smoke."

December 16, 1993, presentation at the National ETS Conference (Washington, DC), entitled "Scientific assessment of the EPA report, Respiratory effects of passive smoking: lung cancer and other disorders."

March 17, 1994, presentation to the House of Representatives Committee on Energy and Commerce Subcommittee on Health and the Environment (chair, Congressman Henry Waxman).

May 11, 1994, presentation on behalf of the Tobacco Institute to the Senate Committee on Environment and Public Works, Subcommittee on Clean Air and Nuclear Regulation (chair, Senator Joseph Lieberman). Written replies to additional questions from Senators Lieberman, Faircloth and Lautenberg.

May 23, 1994. News Conference on Second-hand Smoke. National Press Club, Washington DC.

August 13, 1994. Comments on Environmental Tobacco Smoke: work with experimental animals. Before the Occupational Safety and Health Administration, written response to Proposed Rule on Indoor Air Quality (59 Federal Register 15968, April 5, 1994).

August 13, 1994. Comments on Environmental Tobacco Smoke: Repace and Lowrey. Before the Occupational Safety and Health Administration, written response to Proposed Rule on Indoor Air Quality (59 Federal Register 15968, April 5, 1994).

January 17-19, 1995. Comments on Environmental Tobacco Smoke: work with experimental animals. Before the Occupational Safety and Health Administration, verbal response to Proposed Rule on Indoor Air Quality, before the Honorable John Vittone, Administrative Law Judge. Moderator of RJR panel.

October 10, 1995. Presentation "ETS and cancer: epidemiology and laboratory studies". World Association of Societies of Pathology, Auckland, New Zealand.

March 25, 1997. Deposition in re Mike Moore, Attorney General ex. rel., State of Mississippi tobacco litigation.

May 22, 1997. Deposition in Norma R. Broin, et al. vs. Philip Morris Companies, Inc. et al. (Circuit Court of the 11th Judicial Circuit and for Dade County, Florida. Case No. 91-49738 CA 22).

September 25, 1997. Trial testimony in Norma R. Broin et al. vs. Philip Morris Companies, Inc. et al., (Circuit Court of the 11th Judicial Circuit and for Dade County, Florida. Case No. 91-49738 CA (22). Dade County Courthouse, Miami, Florida.

March 10, 1998. Trial testimony in Dunn & Wiley v. RJR Nabisco Holdings Corporation, et al. (State of Indiana, County of Delaware. Cause No. 18D01-9305-CT-06). Delaware County Courthouse, Muncie, Indiana.

November 10, 1998. Deposition in Iron Workers Local Union No. 17 Insurance Fund and its Trustees et al. v. Philip Morris, Inc. et al. (United States District Court for the Northeastern District of Ohio Eastern Division, Civil Action No. 1:97CV1422)

December 2/3, 1998. Presentation "Animal models of human lung carcinogenesis" to the National Toxicology Program, Raleigh, North Carolina.

May 26, 1999. Trial testimony in the Estate of Burl Butler, et al., v. Philip Morris Inc., et al. Civil Action No. 94-5-53, Ellisville, Mississippi.

August 31, 1999. Presentation to the Office of Pesticide Programs, Environmental Protection Agency: "Alternative Risk Mitigation Measures for the use of Aluminum and Magnesium Phosphide Products" (on behalf of the Tobacco Association of the United States).

July 26, 2000. Deposition in American Environmental Safety Institute v. Philip Morris, Incorporated. et al. (Los Angeles County Superior Court Case No. BC 194217).

March 9, 2001. Deposition in Blue Cross and Blue Shield of New Jersey Inc. et al. v. Philip Morris Incorporated et al. (United States District Court, Eastern District of New York, Case No. 98 Civ. 3287 JBW).

June 27, 2001. Deposition in Jocelyn Tomkin v. The American Tobacco Company, et al. (United States District Court for the Northern District of Ohio, Eastern Division. Civ. Action No. 5:94-CV-1302, Duces Tecum.).

July 31, 2001. Deposition in Christa J. Blankenship and Mae Sibo v. Philip Morris Incorporated et al. (Civil Action No. 00-C-6000 Circuit Court, Ohio County, West Virginia).

August 17, 2001. Deposition in United States of America v. Philip Morris Incorporated, et al. (Civil Action No. 99-CV-02496-GK), under Rule 30(b)(6) of the Federal Rules of Civil Procedure.

May 22, 2002. Deposition in Devin Daniels, et al. v. Philip Morris Incorporated, et al. (San Diego Superior Court, case No. 719446, Class Action).

June 27, 2002. Deposition in United States of America v. Philip Morris Incorporated, et al. (Civil Action No. 99-CV-02496-GK), under Rule 30(b)(6) of the Federal Rules of Civil Procedure.

July 18, 2002. Deposition in United States of America v. Philip Morris Incorporated, et al. (Civil Action No. 99-CV-02496-GK).

August 1, 2002. Deposition in United States of America v. Philip Morris Incorporated, et al. (Civil Action No. 99-CV-02496-GK).

November 14, 2002. Deposition in Liebstein v. American Tobacco Company, et al. Nassau County, NY.

REVIEWER

American Industrial Hygiene Association Journal
Cancer Research
National Institutes of Health (grant reviewer)
Inhalation Toxicology (Editorial board).
Pharmacogenetics and Genomics
Regulatory Toxicology and Pharmacology
Toxicologic Pathology
Toxicological Sciences
Toxicology

MISCELLANEOUS

Member of the Editorial Board of the Journal Inhalation Toxicology.
Invited speaker on Fundamentals of Toxicology, Summit School, Winston-Salem, NC.

Carson Watts Consulting - Chris Coggins, Ph.D., DABT - Board Certified Toxicologist
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